position: EnglishChannel > Sci-Tech News > Article

72yh.com: Shanghai institute shares all SARS-CoV-2 expression plasmids

Source: International Communication Center for Science & Technology| 2020-06-24 14:26:59| Author: Wang Chuan& China.org

本文地址:http://www.433nsb.com/English/ChinaNews/2020-06/24/content_962500.shtml
文章摘要:72yh.com,既然敢挑战九九避开了眼目,sun1.com ,是king通缉要犯。

A staff member displays samples of the COVID-19 inactivated vaccine at Sinovac Biotech Ltd., in Beijing, capital of China, March 16, 2020. [Photo/Xinhua]

On June 17, the National Center for Protein Science Shanghai made expression plasmids of all 29 proteins encoded by SARS-CoV-2 available to scientists around the world through a Protein Bank Program (PBP), according to the Shanghai Advanced Research Institute of the Chinese Academy of Sciences.

Rao Zihe, an academician of the Chinese Academy of Sciences, and other researchers led the research on the expression plasmids of all 29 proteins encoded by SARS-CoV-2, the virus that causes COVID-19.

The study of the 29 proteins is crucial to the analysis of pathogenic mechanism, vaccine development, reagent detection, and antibody and drug development.

Experts said the first phase of the PBP is mainly focused on a protein expression plasmid bank, which provides the storage and delivery service of protein expression plasmids. The COVID-19 virus genome consists of less than 30,000 bases and can encodes 29 proteins, including 16 non-structural proteins, four structural proteins and nine auxiliary proteins. Among them, NSP7, NSP8, and NSP12 (all three are non-structural proteins) form RNA-dependent RNA polymerase complexes, which play an important role in virus replication and transcription cycle. NSP5, a 3C proteolytic enzyme, can liberate most other NSP proteins from the protein chain, and is considered to be an important target for the research of antivirus drugs. Four structural proteins, S, E, M, and N, form the outer layer of the coronavirus and protect the internal RNA, in which the spike (S) protein can help the virus invade cells.

To increase China's capabilities of responding to public health crisis, the Shanghai Advanced Research Institute of the Chinese Academy of Sciences established the Protein Bank Program.

(You can also read it at: http://www.zas.qqw55.com/china/2020-06/24/content_76198185.htm)

Editor:龙云

Top News

Researchers discover mechanism that makes COVID-19 more severe in diabetics

Brazilian researchers have discovered one of the causes of severe COVID-19 in diabetic patients. Laboratory experiments showed that the higher level of blood sugar in these patients is captured by monocytes, a type of defense cell, and serves as a source of additional energy for the coronavirus to replicate more than in a healthy organism. In response to the increased viral load, the monocytes release large amounts of pro-inflammatory cytokines with several effects including lung cell death.

A Future to Expect: International S&T Community Expresses High Hope in Cooperation with Peers in China English

According to the latest news from Science and Technology Daily (April 14th), two COVID-19 inactivated vaccines were just approved for a phase I & II combined clinical trial by the National Medical Products Administration (NMPA) of China, making them the first batch in this category. The two vaccines were developed respectively by Wuhan Institute of Biological Products Co., Ltd of Sinopharm and Sinovac Research & Development Co., Ltd together with research institutes.

Copyright ? Science and Technology Daily, All Rights Reserved

mailto: yuhy@www.433nsb.com

68kcd.com msc977.com sblive17.com tyc295.com 乐橙娱乐代理官网
kcd49.com 44sb.com 896sun.com 551sb.com am32.com
VNS9.com 91sun.com 79msc.com sun361.com sb575.com
辉煌真人赌大小 sun352.com 申博官网娱乐开户登入 687sb.com kcd82.com